I would change it after the first two hours and then put in synthetic. Run it the rest of the season on your second oil change and then change it again at the end of the season when you put it away. That way, you can pretty much bet you've gotten any small particles out from when it was mfg. Opinions will very on this topic especially when it comes to oil.
Well it is about opinions on this site. So I will give mine, it is based on reference from a friend who rebuilds engines for >30 years.
I am not going to get into the synthetic vs conventional debate, use what your manual recommends.
Some manufactures do recommend synthetic, some don't. I can tell you that Yamaha does not make any mention of synthetic oil. I will not be using synthetic oil in my new purchase.
What I will recommend is that you break it in with conventional oil, for the first 50 hours. This allows the various moving parts, esp rings, to wear in, seat, etc. I am not an engine expert, but my friend is, just sharing what he passed on to me.
After you break it in, use what your op manual recommends, may even recommend a synthetic.